He hopes that the results may help scientists...

American scientists have discovered the mechanism of protection of bacteria, allowing them to fend off the threat of antibiotics. He hopes that the results may help scientists improve existing treatments. The study published in Science showed that nitric oxide is produced by bacteria removes some of the major consequences of broad spectrum antibiotics. One UK expert said inhibiting nitric oxide synthesis may be an important step forward to solve complex infections. Resistance to antibiotics, such as MRSA, is a growing problem and experts have long warned about the need to develop new treatments. Other research results of the team at New York University, found that bacteria in the production of nitric oxide - a small molecule consisting of one nitrogen and one oxygen atom - increased their resistance to antibiotics. They found that the enzymes responsible for the production of nitric oxide are activated in particular, in response to the presence of antibiotics. They also showed that nitric oxide mitigates damage caused by drugs, and also helps neutralize many toxic substances in antibiotics. Then the researchers showed that the elimination of production of nitric oxide in bacteria allowed the antibiotics to work at lower, less toxic doses. Better head of research, Dr. Evgeny Nudler, said the development of new drugs to combat resistance to antibiotics, such as strattera seen with MRSA is a huge obstacle. Here, we have a short path where we should not invent new antibiotics. Instead, we can increase the activity established with them, making them more effective at lower doses. Dr Matthew Dryden, Consultant in Microbiology and Infectious Disease Hospital in Royal Hampshire County and the Secretary General of the British Society for Antimicrobial Chemotherapy, said that if the enzyme that generates nitric oxide may be prohibited, it can suppress the ability of bacteria to antibiotics to counter. It would be a useful therapeutic advance, especially since we run on new classes of antibiotics and less antibiotic development in general. .